Serious heart indications which include rapidly, irregular, or pounding heartbeats; fluttering inside your chest; shortness of breath; and sudden dizziness, lightheadedness, or passing out;

Usage of opioid analgesics for prolonged time frame through pregnancy for healthcare or nonmedical reasons may lead to physical dependence in the neonate and neonatal opioid withdrawal syndrome shortly soon after delivery

The overall prevalence of sulfite sensitivity in the final population is unfamiliar and doubtless low. Sulfite sensitivity is viewed additional routinely in asthmatic than in nonasthmatic individuals. Utilization of DILAUDID Oral Resolution and DILAUDID Tablets is contraindicated in individuals with hypersensitivity to sulfite-made up of medicines.

Some dosage kinds may well have trace amounts of sodium metabisulfite, which can cause allergic reactions

In the event the response to an opioid antagonist is suboptimal or only temporary in nature, administer additional antagonist as directed via the product or service's prescribing information and facts.

Serotonin syndrome: Conditions of serotonin syndrome, a perhaps daily life-threatening situation, have already been described throughout concomitant use of opioids with serotonergic medicines.

Assess Just about every individual's chance for opioid habit, abuse, or misuse before prescribing DILAUDID INJECTION and check all sufferers obtaining DILAUDID INJECTION for the event of these behaviors and situations. Challenges are amplified in patients with a personal or relatives background of compound abuse (which include drug or Alcoholic beverages abuse or habit) or psychological sickness (e.

The hydromorphone in DILAUDID Oral Alternative this content or DILAUDID Tablets may well raise the frequency of seizures in sufferers with seizure Ailments, and should increase the hazard of seizures taking place in other scientific configurations connected to seizures.

Hydromorphone substantial-potency injection is very concentrated Option of hydromorphone, a potent Routine II controlled opioid agonist intended for use in opioid-tolerant patients; It isn't to become Check This Out baffled with regular parenteral formulations of hydromorphone or check over here other opioids; overdose and death could result

Use the bottom productive dosage for your shortest period of time per specific client remedy goals. Reserve titration to bigger doses Source of DILAUDID for clients in whom lower doses are insufficiently productive As well as in whom the anticipated advantages of employing a higher dose opioid clearly outweigh the substantial threats. (2.1, 5)

DILAUDID INJECTION is contraindicated in individuals with regarded or suspected gastrointestinal obstruction, together with paralytic ileus.

Prevent use when having any oral drug that may be depending on threshold concentrations for efficacy. Interactions shown are agent examples and do not consist of all achievable medical examples.

The have a peek here dosage is predicated in your health-related condition and reaction to remedy. Don't improve your dose, go ahead and take medication a lot more frequently, or just take it for an extended time than prescribed. Effectively stop the medication when so directed.

Aged individuals (aged 65 a long time or more mature) could possibly have amplified sensitivity to hydromorphone. Generally, use warning when selecting a dosage for an elderly affected person, ordinarily setting up for the very low conclude in the dosing selection, reflecting the increased frequency of lessened hepatic, renal, or cardiac operate and of concomitant illness or other drug therapy.